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Раннее формирование микробиоты – какие ингредиенты работают лучше всего



✏️ Поднимем сегодня сложный вопрос о ранней модуляции микробиоты. Чтобы отделить доказательную базу от маркетинга, обратимся к трем большим работам, в которых собран значительный опыт врачей и исследователей:



- Мета-анализ 23 РКИ – Delcourt H, Verbrugghe L, Vandenplas Y, Huysentruyt K. Systematic review and meta-analysis of randomized controlled trials on pre-, pro-, post- and synbiotic supplementation in follow-on formula. Clinical Nutrition. 2025;51:101-114.

- Сетевой мета-анализ – Mansouri F, Mardani M, Rezapour M, Bordoni L, Gabbianelli R. Evaluating the bifidogenic effect of various infant formula supplementations: a systematic review and network meta-analysis of randomized controlled trials. Journal of Developmental Origins of Health and Disease. 2025;16:e35. doi:10.1017/S2040174425100196

- Рекомендации ESPGHAN – Dinleyici EC, et al. (ESPGHAN Special Interest Group on Gut Microbiota and Modifications). Recommendations on the health outcomes of infant formula supplemented with biotics by the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition Special Interest Group on Gut Microbiota and Modifications. Journal of Pediatric Gastroenterology & Nutrition. 2025; August.

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